Sinta Murlistyarini
School of Medicine Universitas Brawijaya, Indonesia
Title: 15% Glycolic acid chemical peeling for periorbital dark circle
Biography
Biography: Sinta Murlistyarini
Abstract
Introduction: Periorbital dark circle is a common condition that involves darkening of the upper and lower eyelid skin. Dark circles are caused by multipe etiologic factors that include dermal postinflammatory hyperpigmentation, dermal melanin deposition, superficial location of vasculature, periorbital edema, and shadowing due to skin laxity. It is often refractory to treatment. Multiple treatment modalities have been used for periorbital hyperpigmentation with unsatisfactory result.
Case: A 28 years-old Javanese female came with chief complaint of dark circles around her eyes. She had a personal history of atopy. Dermatological examination revealed bilateral periorbital hyperpigmented patch with thickening and fine lines involving her upper and lower eyelids. Pre-peel treatment with 8% glycolic acid once daily and sunblock SPF33 were given since 2 weeks before peeling treatment. 15% glycolic acid chemical peeling was performed. After two series 3-weekly interval chemical peeling, there was improvement in hyperpigmentation of 25-50% Physician Global Assessment and scored 3 in patient’s Visual Analog Scale. No side effect was noted.
Discussion: Periorbital dark circle due to atopic dermatitis are believed to be caused by accumulation of fluid due to facial allergy, rubbing and scratching the skin around the eyes. Glycolic acid may contribute through various ways, as anti-inflammatory, keratolytic, and antioxidant effects. Glycolic acid accelerates collagen synthesis, decreasing Ca ion and modulates matrix degradation.