Candice Ansorge
MCU-FDTMF Dept. Of ORL-HNS, Philippines
Title: Otorhinologic Manifestations of Human Immunodeficiency Virus infection in a National Tertiary Infectious Disease Hospital
Biography
Biography: Candice Ansorge
Abstract
This study aims to determine the prevalence of Ear Nose throat (ENT) complications in patients with Human Immunodeficiency Virus (HIV) and its association with age, sex, CD4 count, and antiretroviral treatment. A total of 360 subjects were included in the study, age ranged from 19 to 65 years with a mean age of 32.87 years, confirmed to be with HIV, on antiretroviral (ARV) drugs > than 3 months, seen at the in-patient and outpatient department of H4 and TB ward in a National Tertiary Infectious Disease Hospital from February to July, 2019 were included. Majority were males at 97%. Otologic manifestations were SNHL (6.1%), AOM (1.1%), BPPV (1.9%), CSOM (1.4%), Malignant Otitis Externa (0.3%) and CHL (0.6%). Similar number of patients had acute rhinitis, allergic rhinitis and acute rhinosinusitis at 1.1%. Oropharyngeal manifestations were oral candidiasis (1.1%), aphthous stomatitis (0.8%), tonsillar papilloma (0.3%) and chelitis (0.3%). Laryngeal manifestations noted were LPRD (1.4%), acute laryngitis (0.3%), vocal cord paralysis (0.3%), chronic laryngitis (0.3%) and candidiasis (0.3%). TB adenitis was noted in 37 (10.3%) patients. There was a significant association noted between ARV treatment and baseline and current CD4 counts with ENT complications as proven by all p values <0.01. The duration of ARV treatment was significantly longer among those with complications than those without with a mean of 3.78 years and 2.64 years respectively. For baseline and current CD4 count, significantly higher proportion of subjects with complications had lower baseline CD4 count. On the other hand, age, sex and BMI were not significantly associated with ENT complications (p>0.05).